5-Methoxytryptoline

Overview

5-Methoxytryptoline acts as a modulator of the Serotonin transporter complex, as well as a ligand for the 5-HT 2A and 5-HT 2C receptors, with K i values of 130 nM and 140 nM for the 5-HT 2A and 5-HT 2C receptors, respectively. 5-Methoxytryptoline inhibits the active uptake of Serotonin ( HY-B1473A ) and Tryptamine ( HY-B2132 ) in platelets. 5-Methoxytryptoline induces behavioral excitation, cortical electroencephalographic desynchronization, and dose-dependent elevation of plasma prolactin , followed by behavioral sedation and partial recovery of cortical electroencephalographic voltage. 5-Methoxytryptoline antagonizes Reserpine ( HY-N0480 )-induced sedation, reduced locomotor activity, and hypothermia. 5-Methoxytryptoline exerts dose-dependent effects on behavior and cortical electroencephalographic activity in freely moving rats. 5-Methoxytryptoline can be used in depression-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Serotonin Transporter

Product Information

• Catalog No.: HY-177797
• CAS No.: 30439-19-1
• Molecular Formula: C12H14N2O
• Molecular Weight: 202.26
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source