PJ17

Overview

PJ17 is a potent dual-target inhibitor of AChE and GSK-3β , with IC 50 values of 8.84 μM and 4.19 μM, respectively. PJ17 shows no significant neurotoxic effect in primary cerebellar granule neuron cultures. PJ17 serves as a template for the design of multitarget drugs. PJ17 can be used for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > GSK-3

Product Information

• Catalog No.: HY-181811
• CAS No.: 2248983-31-3
• Molecular Formula: C15H13FN4O2
• Molecular Weight: 300.29
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source