PROTAC DHFR Degrader-1

Overview

PROTAC DHFR Degrader-1 is a selective PROTAC degrader targeting Plasmodium falciparum DHFR-TS with a K i of 2.01 nM. PROTAC DHFR Degrader-1 exhibits no inhibitory activity against human DHFR and suppresses the growth of Plasmodium falciparum . PROTAC DHFR Degrader-1 can be used for the research of Plasmodium falciparum and malaria. (Pink: Dihydrofolate reductase (DHFR) ligand ( HY-153007 ); Blue: MDM-2/p53 ligand ( HY-15676 ); Black: linker).

Application

Products | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Plasmodium Infection | Products > Disease Areas > Infection | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Ligands for E3 Ligase | Products > Signaling Pathways > Dihydrofolate reductase (DHFR) | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-181813
• CAS No.: 3077918-47-6
• Molecular Formula: C53H60Cl2F2N8O9
• Molecular Weight: 1061.99
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source