AgrC-IN-1 is an AgrC inhibitor with an IC 50 of 3.5 μM against Staphylococcus aureus AgrC. AgrC-IN-1 competitively binds to AgrC, inhibiting its autophosphorylation activity in Staphylococcus aureus . AgrC-IN-1 inhibits quorum sensing in Staphylococcus aureus , blocking virulence factor production. AgrC-IN-1 can be used for the research of Staphylococcus aureus infections.
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