DDR1/2 IN-4 (Compound 37) is a selective dual DDR1 and DDR2 kinase inhibitor, with a pK i of 8.6 for DDR1 and a pK i of 8.2 for DDR2 . DDR1/2 IN-4 functionally inhibits the kinase activities of DDR1 and DDR2 . DDR1/2 IN-4 inhibits the release of MCP-1 . DDR1/2 IN-4 can be used in studies related to idiopathic pulmonary fibrosis.
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