F44-S101

Overview

F44-S101 is an orally active, potent, and selective gut-restricted FXR antagonist with an IC 50 of 0.48 μM and lipid-lowering activity. F44-S101 selectively antagonizes intestinal FXR , feedback-activates hepatic FXR , promotes cholesterol metabolism and reduces lipid accumulation. F44-S101 decreases total cholesterol , triglyceride and low-density lipoprotein cholesterol levels. F44-S101 can be used in studies related to hyperlipidemia.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Hyperlipidemia | Products > Disease Areas > Hypercholesterolemia | Products > Disease Areas > Hypertriglyceridemia | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > FXR

Product Information

• Catalog No.: HY-181876
• CAS No.: 3124701-00-1
• Molecular Formula: C27H25ClN2O6S2
• Molecular Weight: 573.08
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source