Multi-target kinase-IN-10

Overview

Multi-target kinase-IN-10 (Compound 6l) is an orally active, blood-brain barrier-permeable, selective, reversible, and competitive MAO-B inhibitor with an IC 50 of 0.0053 μM. Multi-target kinase-IN-10 competes with substrates for binding to the active site of MAO-B , chelates Cu 2+ ions, inhibits Cu 2+ -induced ROS production, and reduces the release of NO , TNF-α , and IL-1β . Multi-target kinase-IN-10 ameliorates Parkinson's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-181937
• CAS No.: 3022330-81-7
• Molecular Formula: C17H13FN2O2
• Molecular Weight: 296.30
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source