CN016 is a neuroprotective agent. CN016 inhibits the elevation of pro-inflammatory cytokines G-CSF , GM-CSF and IL-6 induced by Oxaliplatin ( HY-17371 ). CN016 suppresses Paclitaxel ( HY-B0015 )-induced inflammatory responses and immune cell infiltration into sensory neurons. CN016 protects neurons from Paclitaxel ( HY-B0015 )-induced neurotoxic damage. CN016 protects mice against Oxaliplatin -induced peripheral neuropathy.
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