ZLWH-67

Overview

ZLWH-67 is a β-Carboline derivative and Antibacterial agent. ZLWH-67 inhibits DNA synthesis, suppresses biofilm formation, and increases reactive oxygen species ( ROS ) levels. ZLWH-67 exhibits potent in vitro antibacterial activity against MRSA ( MIC = 0.5-4 μg/mL), S. epidermidis ( MIC = 4 μg/mL), E. faecalis ( MIC = 4-8 μg/mL), and S. pneumoniae ( MIC = 16 μg/mL). ZLWH-67 displays anti- MRSA effects in murine skin and pneumonia infection models.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Streptococcus Pneumoniae Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-182022
• CAS No.: 3083425-49-1
• Molecular Formula: C24H20N4O4
• Molecular Weight: 428.44
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source