ClpP agonist 1

Overview

ClpP agonist 1 is a Staphylococcus aureus ClpP ( SaClpP ) agonist with an EC 50 of 1.44 μM, K d values of 2.95 μM (isothermal titration calorimetry) and 18 μM (bio-layer interferometry), and a low drug resistance frequency. ClpP agonist 1 reduces bacterial load, shrinks infected area and improves histopathological outcomes in a mouse skin infection model. ClpP agonist 1 can be used for the research of Methicillin ( HY-121544 )-resistant Staphylococcus aureus (MRSA) skin infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > ClpP

Product Information

• Catalog No.: HY-182033
• CAS No.: 2761081-10-9
• Molecular Formula: C24H21F5N4O
• Molecular Weight: 476.44
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source