Phloretin

Overview

Phloretin, a type of natural phenol found in the peels of apples, is a dihydrochalcone that shows beneficial effects on diabetes. Phloretin has whitening, freckle removal, anti-aging, strong antioxidant, and photoprotective effects. It can also inhibit the activity of matrix metalloproteinase (MMP-1) and elastase, which can degrade skin connective tissue and play an important role in the process of skin photoaging. Phloretin has excellent immunosuppressive and anti-inflammatory effects. Phloretin can significantly inhibit the levels of nitrogen oxide, prostaglandin E2, IL-6, TNF-α, iNOS and COX-2, inhibit the nuclear translocation of NF-JB subunit p65 protein, and reduce phosphorylation in the MAPK pathway. It can be used in facial masks, skin creams, lotions and essences.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Endocrinology and Metabolic Disease | GLUT(Glucose transporter)

Product Information

• Catalog No.: B2703-294580
• CAS No.: 60-82-2
• Molecular Formula: C15H14O5
• Molecular Weight: 274.27
• Purity: >98%
• Storage: Store at 2-8°C
• Solubility: Soluble in Acetonitrile (Slightly), Methanol (Slightly)

Source

Original product source