D-473

Overview

D-473 is an orally active, blood-brain barrier penetrant and serotonin-preferring reuptake inhibitor. D-473 inhibits serotonin, dopamine and norepinephrine transporters, and significantly elevates the extracellular levels of these three neurotransmitters in rat brain regions. D-473 exhibits definite antidepressant-like activity without inducing motor activation. D-473 is widely used in studies related to major depressive disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Serotonin Transporter | Products > Signaling Pathways > Dopamine Transporter

Product Information

• Catalog No.: HY-182247
• CAS No.: 1632000-05-5
• Molecular Formula: C26H27F2NO3
• Molecular Weight: 439.49
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source