Negundoside is an iridoid glycoside compound. Negundoside exhibits hepatoprotective effects, reduces ROS , lipid peroxidation and intracellular calcium ion levels, and prevents the decrease of mitochondrial membrane potential ( MMP ) and apoptosis ( apoptosis ). Negundoside has neuroprotective effects, improves behavioral deficits, alleviates oxidative damage, and ameliorates cerebral infarction. Negundoside also possesses antibacterial and antiparasitic activities.
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