DT-5461

Overview

DT-5461 is an IL-1 and TNF-α antagonist. DT-5461 competitively binds lipid A-binding sites on macrophage receptors, blocks LPS ( HY-D1056 )-initiated signaling, inhibits LPS-induced cytokine release, prevents LPS-induced serum cytokine production in mice , and protects against LPS-induced lethal endotoxemia. DT-5461 can be used for the research of lethal endotoxemia, medullary tubular mammary carcinoma, poorly differentiated colon adenocarcinoma, squamous-cell lung carcinoma, and gelatinous gastric adenocarcinoma.

Application

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Product Information

• Catalog No.: HY-182377
• CAS No.: 123598-19-6
• Molecular Formula: C73H133N4O22P
• Molecular Weight: 1449.82
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source