NLX-219 is a selective agonist of the 5-HT 1A with a pK i of 10.21. NLX-219 activates ERK1/2 phosphorylation, inhibits adenylyl cyclase activity, promotes β-arrestin recruitment. NLX-219 can be used for the research of neurological disease .
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Arrestin | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > ERK | Products > Signaling Pathways > Adenylate Cyclase
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