BTS 72664

Overview

BTS 72664 is a broad-spectrum, non-sedating, orally effective anticonvulsant. Its anticonvulsant effect mainly arises from enhancing GABA A receptor ( GABA A receptor )-mediated chloride channel currents, while it exerts weak blocking effects on Na + channels ( K i = 350 μM) and NMDA receptors ( NMDA receptor ) ( IC 50 = 43 μM). BTS 72664 prevents the elevation of extracellular glutamate, glycine and serine concentrations in neurons, reduces cerebral infarct size, promotes functional recovery, prevents multiple types of epileptic seizures, and has low sedative potential. BTS 72664 can be used for the research of epilepsy, stroke and migraine.

Application

Products | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Epilepsy | Products > Disease Areas > Migraine | Products > Disease Areas > Ischemic Stroke | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > GABA Receptor | Products > Signaling Pathways > Sodium Channel | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-182548
• CAS No.: 165383-52-8
• Molecular Formula: C13H11ClN4O
• Molecular Weight: 274.71
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source