Nandinine

Overview

Nandinine is an orally active derivative of Berberine ( HY-N0716 ). Nandinine enhances AMPK activity, inhibits the activation of IKKβ/NF-κB , and regulates the phosphorylation of IRS-1 . Nandinine reverses the abnormal production of adipokines, promotes insulin-mediated glucose uptake, and alleviates insulin resistance. Nandinine improves glucose tolerance and increases the insulin sensitivity index in mice. Nandinine can be used in studies related to insulin resistance.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Others | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > NF-κB | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > IKK | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-182558
• CAS No.: 572-76-9
• Molecular Formula: C19H19NO4
• Molecular Weight: 325.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source