CJ-14897 is a cytokine production inhibitor, with IC 50 values of 0.059 μM and 0.59 μM for IL-1β and TNF-α production, respectively, and an IC 50 of 180 μM for leucine uptake. CJ-14897 is isolated from the fermentation broth of the basidiomycete Marasmius strain CL21624.
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