SM-11044

Overview

SM-11044 is a β-adrenoceptor agonist with K i values of 18.1 μM (β 1 ), 4.1 μM (β 2 ) and 1.3 μM (β 3 ), showing higher binding selectivity for the β 3 -adrenoceptor. SM-11044 stimulates cAMP accumulation in cells expressing this receptor. SM-11044 mediates ileal relaxation, tracheal relaxation, pulmonary parenchymal relaxation, increased right atrial heart rate and adipocyte lipolysis.

Application

Products | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Heart Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-182640
• CAS No.: 142784-65-4
• Molecular Formula: C22H28BrFN2O4
• Molecular Weight: 483.37
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source