CRF1 receptor antagonist-2

Overview

CRF1 receptor antagonist-2 is an orally active, blood-brain barrier permeable CRF1 receptor antagonist, with an IC 50 of 4 nM in CHO-K1 cell membranes and an IC 50 of 7 nM in rat brain cell membranes. CRF1 receptor antagonist-2 exerts anxiolytic effects in swim stress-loaded rats. CRF1 receptor antagonist-2 can be used in studies related to stress-induced anxiety.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Anxiety or Fear-Related Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > CRFR

Product Information

• Catalog No.: HY-182645
• CAS No.: 441060-02-2
• Molecular Formula: C22H27ClN4O
• Molecular Weight: 398.93
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source