PROTAC BRD4 Degrader-46

Overview

PROTAC BRD4 Degrader-46 is a heterobifunctional BRD4 PROTAC degrader. PROTAC BRD4 Degrader-46 binds to both BRD4 and CRBN , thereby triggering ubiquitination and proteasomal degradation of BRD4 . PROTAC BRD4 Degrader-46 downregulates the levels of downstream BRD2 , BRD3 and MYC . PROTAC BRD4 Degrader-46 can be used in the research of cancers such as multiple myeloma. (Pink: BRD4 ligand ( HY-78695 ); Blue: Cereblon E3 ligase ligand; Black: linker).

Application

Products | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Multiple Myeloma | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > c-Myc

Product Information

• Catalog No.: HY-182801
• CAS No.: 2766179-68-2
• Molecular Formula: C35H34ClN9O4S
• Molecular Weight: 712.22
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source