AGN 225660

Overview

AGN 225660 is a multi-prostanoid receptor antagonist with human IC 50 values of 70, 70, 5, 220 and 180 nM for EP1 , EP4 , TP , DP1 , FP . AGN 225660 inhibits secretion of RANTES , IL-8 , MCP-1 , IL-12p70 , and IL-23 . AGN 225660 exhibits good ocular bioavailability and reduces ocular inflammation linked to phacoemulsification surgery and uveitis.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-183037
• CAS No.: 1354060-46-0
• Molecular Formula: C20H27ClN2O3
• Molecular Weight: 378.89
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source