UCP1173

Overview

UCP1173, propargyl-linked antifolate , is an antibacterial agent. UCP1173 inhibits DHFR enzymes , with IC 50 values of 0.014 μM for DfrB, 0.19 μM for DfrG, 0.27 μM for DfrA, and 0.091 μM for DfrK. UCP1173 inhibits growth of Staphylococcus aureus clinical isolates carrying dfrA, dfrG, or dfrK resistance genes. UCP1173 can be used for the research of bacterial infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Dihydrofolate reductase (DHFR) | Products > Signaling Pathways > Antifolate

Product Information

• Catalog No.: HY-183053
• CAS No.: 1922152-09-7
• Molecular Formula: C24H24N4O3
• Molecular Weight: 416.48
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source