NAMPT activator-10

Overview

NAMPT activator-10 (Compound B11) is an orally active NAMPT activator with a target K d value of 0.64 μM. NAMPT activator-10 activates the rate-limiting enzyme in NAD + biosynthesis and promotes intracellular NAD + synthesis. NAMPT activator-10 reduces lactate accumulation, enhances glycogen storage in the liver and muscle, increases tissue ATP production, improves exercise endurance and muscle strength, and exerts a protective effect against fatigue-induced muscle damage in mouse fatigue models. NAMPT activator-10 can be used in studies related to muscle fatigue.

Application

Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Muscle Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > NAMPT | Products > Signaling Pathways > ATP Synthase

Product Information

• Catalog No.: HY-183148
• CAS No.: 2237269-22-4
• Molecular Formula: C20H20N4O4S
• Molecular Weight: 412.46
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source