Acetylgliotoxin

Overview

Acetylgliotoxin (Gliotoxin monoacetate) is a farnesyltransferase (FTase) inhibitor with an IC 50 of 4.4 μM against human targets. Acetylgliotoxin inhibits the growth of fungal , bacterial , and viral pathogens; it binds to free protein thiols and induces ROS production. Acetylgliotoxin increases the survival rate of Caenorhabditis elegans infected with Candida albicans , but exhibits toxicity at higher concentrations. Acetylgliotoxin is applicable to research related to Candida albicans infections.

Application

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Product Information

• Catalog No.: HY-183421
• CAS No.: 146016-64-0
• Molecular Formula: C15H16N2O5S2
• Molecular Weight: 368.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source