MMH409

Overview

MMH409 is a selective HDAC8 inhibitor, with an IC 50 value of 23 nM and a K d value of 3.5 nM against human HDAC8 , and an IC 50 value of 11.64 μM against Schistosoma mansoni HDAC8 . MMH409 reduces the viability of newly transformed schistosomula and adult worms of Schistosoma mansoni in vitro. MMH409 serves as a biological probe to investigate the pharmacological knockdown effect of HDAC8 in diseased cells. MMH409 can be used in studies related to neuroblastoma and schistosomiasis<.

Application

Products | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Neuroblastoma | Products > Disease Areas > CNS Neoplasm | Products > Disease Areas > Schistosoma Japonicum Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-183426
• CAS No.: 2704554-86-7
• Molecular Formula: C19H16F6N2O3
• Molecular Weight: 434.33
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source