p38 MAPK-IN-11

Overview

p38 MAPK-IN-11 is a CSBP ( p38 MAPK ) kinase inhibitor with IC 50 values of 0.15 μM (binding activity) and 0.21 μM (inhibitory activity). p38 MAPK-IN-11 shows weak inhibitory activity against PKCα kinase, with an IC 50 of 7.6 μM. p38 MAPK-IN-11 inhibits the production of IL-1 . p38 MAPK-IN-11 also acts as a β-lactam antibiotic potentiator, but has no antibacterial activity itself.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Infection | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > PKC | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-183530
• CAS No.: 152121-51-2
• Molecular Formula: C20H14FN3
• Molecular Weight: 315.35
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source