mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) ( HY-B0450A ). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV + gastric cancer cells via the hypoxia pathway ( HIF‑1α ). mCPX is applicable to research related to EBV-positive gastric cancer .
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