MK-5661

Overview

MK-5661 is an orally potent Na V 1.8 voltage-gated sodium channel inhibitor with an EC 50 of 4.3 nM. MK-5661 selectively inhibits peripheral nociceptive signaling mediators. MK-5661 reduces capsaicin-induced spontaneous nociceptive behaviors in humanized rats and attenuates capsaicin-induced skin flushing responses in rhesus monkeys. MK-5661 is applicable for pain-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-183566
• CAS No.: 2417328-24-4
• Molecular Formula: C18H18F5N5O3S
• Molecular Weight: 479.42
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source