ProAlk01

Overview

ProAlk01 is a protein alkylating agent that serves as a toxin payload for ADCs. ProAlk01 localizes to the cytoplasm and exerts cytotoxic effects mainly by alkylating cytoplasmic proteins rather than binding to DNA. ProAlk01 induces cell cycle arrest, apoptosis , and immunogenic cell death. ProAlk01 can be used in the research of solid tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-183623
• CAS No.: 1296670-84-2
• Molecular Formula: C31H28Cl2N2O4
• Molecular Weight: 563.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source