F-SLOH

Overview

F-SLOH is a brain-penerant and orally active TFEB activator and amyloid-β inhibitor with an IC 50 of 3.4 μM against amyloid-β . F-SLOH promotes nuclear translocation of TFEB, driving autophagy and lysosomal biogenesis. F-SLOH reduces amyloid-β oligomers and Tau aggregates via autophagy lysosomal degradation pathway. F-SLOH can be used for the research of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Tau Protein

Product Information

• Catalog No.: HY-183660
• CAS No.: 1620896-55-0
• Molecular Formula: C30H30ClFN2O3
• Molecular Weight: 521.02
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source