NS3956

Overview

NS3956 is a blood-brain barrier-permeable human α4β2-nicotinic acetylcholine receptor ( nAChR ) agonist ( K i = 0.36 nM). NS3956 induces dopamine release, produces analgesic effects, modulates rotational behavior in 6-OHDA-lesioned rats, and potentiates the effects of SSRI / SNRI in the forced swim test in mice. NS3956 can be used in research related to depression, Parkinson's disease, and acute pain.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > nAChR | Products > Signaling Pathways > Serotonin Transporter

Product Information

• Catalog No.: HY-183666
• CAS No.: 223796-90-5
• Molecular Formula: C10H14ClN3
• Molecular Weight: 211.69
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source