MptpB-IN-3

Overview

MptpB-IN-3 is a selective inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B ( MptpB ) with an IC 50 of 0.19 μM. MptpB-IN-3 blocks MptpB -mediated inhibition of the macrophage MAPK pathway and restores the phosphorylation levels of Erk1/2 and p38 . MptpB-IN-3 exhibits direct anti-tuberculosis activity against Mycobacterium tuberculosis and reduces the Mycobacterium tuberculosis load in mouse macrophages. MptpB-IN-3 can be used for tuberculosis research.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Phosphatase | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-183688
• CAS No.: 3104354-58-4
• Molecular Formula: C22H21FN4O7S2
• Molecular Weight: 536.55
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source