Amentoflavone

Overview

Amentoflavone, a natural flavonoid isolated from the the seed of Ginkgo biloba L, exhibits anti-inflammatory activity, and inhibits NF-κB/DNA binding activity potently along with inhibition of degradation of IκBα and NF-κB translocation into nucleus in TNFα-activated A549 cells. Amentoflavone has the inhibition of LPS-induced NO formation, due to its inhibition of NF-kappaB by blocking degradation, which may be the mechanistic basis of the anti-inflammatory effects of amentoflavone.

Application

Products > Chemistry > Natural Compounds | Products > Drug Discovery > Inhibitor | Flavonoids

Product Information

• Catalog No.: B2703-464494
• CAS No.: 1617-53-4
• Molecular Formula: C30H18O10
• Molecular Weight: 538.46
• Purity: >98%
• Storage: Store in a cool and dry place and at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
• Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)

Source

Original product source