DD-161515

Overview

DD-161515 is a TRPV1/VR1 inhibitor with an IC 50 of 0.7 μM in rats. DD-161515 binds to an allosteric site of TRPV1 distinct from that of capsaicin, blocks channel opening, inhibits receptor-mediated calcium ion influx, reduces the excitability of peripheral sensory nerve fibers, and thereby inhibits nociception induced by heat and transmission of chemically induced pain signals. DD-161515 can be used in studies related to inflammatory pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-183857
• CAS No.: 410080-55-6
• Molecular Formula: C29H37Cl4N5O3
• Molecular Weight: 645.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source