H142/08

Overview

H142/08 is a β1-adrenergic receptor -selective agonist. H142/08 induces concentration-dependent relaxation of isolated rat uterus and acts as a chronotropic stimulant to increase atrial rate, and its effects are effectively antagonized by Pafenolol ( HY-165495 ). H142/08 also antagonizes the chronotropic effect of isoproterenol on isolated rat right atrium, but requires a higher proportion of receptor occupancy to produce sufficient stimulatory effects.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-183859
• CAS No.: 88017-05-4
• Molecular Formula: C22H37N3O6
• Molecular Weight: 439.55
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source