LAF-153

Overview

LAF-153 is a Methionine Aminopeptidase-2 (MetAP-2) inhibitor with human IC 50 values of 0.074 μM and 0.16 μM.LAF-153 has a t-butyl group extending into the innermost portion of the MetAP-2 cleft, a lactam ring coordinated in the enzyme’s shallow surface pocket, and three hydroxyl groups coordinating to the two cobalt ions in the enzyme’s active site.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Aminopeptidase

Product Information

• Catalog No.: HY-183876
• CAS No.: 661482-39-9
• Molecular Formula: C18H32N2O7
• Molecular Weight: 388.46
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source