Zincov

Overview

Zincov is an orally active hydroxamic acid derivative and bacterial metalloproteinase inhibitor. Zincov blocks chloride ion binding by binding to the active site of thermolysin, thereby inhibiting the hydrolysis and blood coagulation reactions catalyzed by this enzyme. Meanwhile, Zincov attenuates cytotoxicity, prevents protein degradation and ZO-1 rearrangement without affecting the functions of other common proteases. Zincov exhibits blood glucose-regulating and antioxidant activities; it reduces blood glucose levels and increases liver dry weight in diabetic rats, but elevates blood glucose levels in normal rats. Zincov is widely used in studies related to cholera and diabetes.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Vibrio Cholerae Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-183878
• CAS No.: 71431-46-4
• Molecular Formula: C12H22N4O5
• Molecular Weight: 302.33
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source