GNF7156

Overview

GNF7156 is a DYRK1A / GSK3B inhibitor, IC 50 values of 100 nM for DYRK1A and 40 nM for GSK3B. GNF7156 inhibits DYRK1A and GSK3B kinase activity and induces NFAT nuclear retention. GNF7156 stimulates beta-cell cycle entry and division and maintains insulin secretory capacity. GNF7156 can be used for the research of type 1 diabetes, and type 2 diabetes.

Application

Products | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 1 Diabetes | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > DYRK | Products > Signaling Pathways > GSK-3

Product Information

• Catalog No.: HY-183955
• CAS No.: 2041071-54-7
• Molecular Formula: C22H22N6O3
• Molecular Weight: 418.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source