3,4,6-Tribromo-5-methylbenzene-1,2-diol (Compound 4) acts as an aldose reductase inhibitor with an IC 50 of 1.15 μg/mL. 3,4,6-Tribromo-5-methylbenzene-1,2-diol blocks the conversion of excessive D-glucose ( HY-B0389 ) to D-sorbitol ( HY-B0400 ) via the polyol pathway. 3,4,6-Tribromo-5-methylbenzene-1,2-diol can be used in studies related to diabetic complications.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Aldose Reductase
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