JMX0207

Overview

JMX0207 is an orally active flavivirus NS2B-NS3 protease inhibitor. JMX0207 showed an IC 50-SLC of 1.3 μM for blocking NS2B-NS3 protein interaction and an IC 50-pro of 8.2 μM for inhibiting protease catalytic activity.. JMX0207 directly binds viral NS3 protease at the NS2B-NS3 interface with a K d of 1.1 μM, blocks viral polyprotein precursor processing, suppresses viral RNA replication and viral protein production. JMX0207 can be used for the study of Zika virus infection and Dengue virus infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Disease Areas > Flavivirus Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > Virus Protease | Products > Signaling Pathways > Dengue Virus

Product Information

• Catalog No.: HY-184048
• CAS No.: 33580-97-1
• Molecular Formula: C13H8ClN3O6
• Molecular Weight: 337.67
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source