ASP8062

Overview

ASP8062 is an orally active, blood-brain barrier-permeable selective GABA B receptor positive allosteric modulator. ASP8062 enhances GABA-mediated activation of GABA B receptors and strengthens GABAergic neurotransmission. ASP8062 reverses Reserpine ( HY-N0480 )-induced myalgia, regulates the sleep-wake cycle, increases delta wave power during non-REM sleep, and impairs motor coordination at high doses. ASP8062 penetrates the central nervous system with a half-life of 40-50 h. ASP8062 can be used in research related to opioid use disorder, fibromyalgia, chronic pain, and alcohol use disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Disease Areas > Chronic Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-184060
• CAS No.: 1704716-36-8
• Molecular Formula: C20H29N3O2S2
• Molecular Weight: 407.59
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source