EYE1090 is an orally active VEGFR2 inhibitor with an IC 50 of 3 nM. EYE1090 inhibits angiogenesis, endothelial migration, VEGFR2 -induced retinal leakage, and reduces choroidal neovascularization lesion size in mice. EYE1090 can be used for the research of age-related macular degeneration, diabetic retinopathy, choroidal neovascularization.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > VEGFR
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