Antimalarial agent 64 is an orally active acridine-based antimalarial derivative and also a rapid-acting inhibitor of hemozoin formation. Antimalarial agent 64 exhibits nanomolar inhibitory activity against field isolates of Plasmodium falciparum and Plasmodium vivax . Antimalarial agent 64 localizes near the digestive vacuole of Plasmodium . Antimalarial agent 64 can be used for the research of malaria.
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