PPAR agonist 8

Overview

PPAR agonist 8 is an orally active pan- PPAR agonist, with K D values of 0.576 μM, 2.06 μM and 1.45 μM for PPARα , PPARγ and PPARδ , respectively. PPAR agonist 8 upregulates the expression of ATP-binding cassette transporter A1 ( ABCA1 ) and promotes cholesterol efflux. PPAR agonist 8 reduces plasma cholesterol levels, decreases cholesterol accumulation in the liver and cholesterol deposition in pancreatic islets, regulates glucose and lipid metabolism, and causes no side effects of weight gain and obesity. PPAR agonist 8 can be used in the research of type 2 diabetes, hepatic steatosis and pancreatic islet dysfunction.

Application

Products | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > ATP-binding cassette (ABC) transporters

Product Information

• Catalog No.: HY-184312
• CAS No.: 1031072-40-8
• Molecular Formula: C13H10N2O4
• Molecular Weight: 258.23
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source