Antifungal agent-166

Overview

Antifungal agent-166 is an anti fungal agent. The combination of Antifungal agent-166 and Fluconazole exerts synergistic bacteriostatic effects against fluconazole-resistant Candida albicans . Antifungal agent-166 exhibits bacteriostatic activity against both Candida glabrata and Cryptococcus neoformans . Antifungal agent-166 reverses the fluconazole resistance of strains by downregulating ergosterol synthesis-related genes, drug resistance-related genes and virulence-related genes. Antifungal agent-166 can enhance the efficacy of Fluconazole in Galleria mellonella and mouse candidiasis models, reduce fungal load and improve survival rate. Antifungal agent-166 can be used in the research of fungal infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Fungal Infection | Products > Disease Areas > Candida Infection | Products > Disease Areas > Cryptococcal Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-184314
• CAS No.: 3122934-62-4
• Molecular Formula: C24H21F2N9O2S
• Molecular Weight: 537.54
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source