KP-457 (GMP)

Overview

KP-457 (GMP) is KP-457 ( HY-110397 ) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 ( ADAM17 ) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10 , and IC 50 s are 11.1 nM ( ADAM17 ), 748 nM ( ADAM10 ), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.

Application

Products | Products > GMP Small Molecules | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-110397G
• CAS No.: 1365803-52-6
• Molecular Formula: C21H24N2O7S2
• Molecular Weight: 480.55
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source