DRAK2-IN-2

Overview

DRAK2-IN-2 is a selective DRAK2 inhibitor with an IC 50 value of 198.5 nM. DRAK2-IN-2 inhibits DRAK2 -mediated phosphorylation of ULK1 at the Ser56 site. DRAK2-IN-2 enhances insulin secretion, increases mitochondrial membrane potential, alleviates Palmitic acid ( HY-N0830 )-induced mitochondrial membrane potential damage and Apoptosis , and improves glucose tolerance in vivo. DRAK2-IN-2 can be used for the research of type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 2 Diabetes | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > DAPK | Products > Signaling Pathways > Ser/Thr Protease | Products > Signaling Pathways > ULK | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-184326
• CAS No.: 3080324-43-9
• Molecular Formula: C22H18N4O2S
• Molecular Weight: 402.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source