NO-Pravastatin

Overview

NO-Pravastatin is a derivative of Pravastatin ( HY-B0165 ) covalently linked with an NO donor moiety, endowing it with dual functions of HMG-CoA reductase ( HMGCR ) inhibition and exogenous nitric oxide (NO) release. NO-Pravastatin activates PPARα/γ and ABCA1 , and inhibits LPS ( HY-D1056 )-induced TNFα production. NO-Pravastatin can be used in research related to gallstones and cardiovascular diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > ATP-binding cassette (ABC) transporters | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > HMG-CoA Reductase (HMGCR)

Product Information

• Catalog No.: HY-184354
• CAS No.: 733034-46-3
• Molecular Formula: C27H43NO10
• Molecular Weight: 541.63
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source