BChE-IN-51 is a selective, blood-brain barrier-permeable, orally active BChE inhibitor with an IC 50 of 0.03 μM against hBChE. BChE-IN-51 reduces ROS production, protects neurons from the toxic effects of hydrogen peroxide and Aβ 1-42 , and alleviates cognitive impairment. BChE-IN-51 can be used for the research of Alzheimer's disease.
Products | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Reactive Oxygen Species (ROS)
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